The continued utilization of benzodiazepines, like VALIUM, might lead to clinically substantial Actual physical dependence. The dangers of dependence and withdrawal raise with extended therapy period and higher day-to-day dose. Abrupt discontinuation or fast dosage reduction of VALIUM just after continued use may well precipitate acute withdrawal r
Diazepam and its metabolites are excreted primarily within the urine, predominantly as their glucuronide conjugates. The clearance of diazepam is twenty to thirty mL/min in youthful Grownups. Diazepam accumulates on various dosing and there is some evidence which the terminal elimination 50 percent-lifestyle is a little bit extended.Bodily dependen
Seizures.Using VALIUM with other medicines used to treat epilepsy can cause an increase in the number or severity of grand mal seizures.Distinctive treatment need to be taken when Valium is used through labor and shipping and delivery, as higher solitary doses may make irregularities in the fetal heart charge and hypotonia, inadequate sucking, hypo
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